Development of oxathiino[6,5-b]pyridine 2,2-dioxide derivatives as selective inhibitors of tumor-related carbonic anhydrases IX and XII
Aiga Grandāne, Alessio Nocentini, Ilona Domračeva, Raivis Žalubovskis, Claudiu T. Supuran
Topics & Concepts
ChemistryHeLaPyridineAdenocarcinomaGene isoformCytosolHuman lungCancer researchBiochemistryStereochemistryEnzymeLungCancerMedicinal chemistryCellInternal medicineGeneBiologyMedicineEnzyme function and inhibitionSynthesis and Catalytic ReactionsChemical Reactions and Mechanisms