Investigation of Poor Solubility of a Salt-Cocrystal Hydrate: A Case Study of the Common-Ion Effect in Betrixaban, an Anticoagulant Drug
Ramesh Devarapalli, Anjaneyaraju Indukuri, Manjunath Bollineni, Amit Mondal, C. Malla Reddy, Ramanaiah Chennuru
Abstract
or drug to coformer ratio.
Topics & Concepts
CocrystalSolubilityChemistryDissolutionHydrateSalt (chemistry)Inorganic chemistryOrganic chemistryMoleculeHydrogen bondCrystallization and Solubility StudiesCrystallography and molecular interactionsDrug Solubulity and Delivery Systems