Increased OIT3 in macrophages promotes PD-L1 expression and hepatocellular carcinogenesis via NF-κB signaling
Jiaqi Wen, Shuai Yang, Guifang Yan, Juan Lei, Xudong Liu, Nan Zhang, Jiangang Zhang, Huan Deng, Lei Wu, Yongsheng Li
Topics & Concepts
BiologyCancer researchHepatocellular carcinomaTumor microenvironmentCarcinogenesisDownregulation and upregulationImmunosuppressionMacrophage polarizationNF-κBSignal transductionCD8Immune systemMacrophageImmunologyCell biologyCancerTumor cellsGeneIn vitroBiochemistryGeneticsImmune cells in cancerMacrophage Migration Inhibitory FactorEpigenetics and DNA Methylation