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Advances in Biocatalytic Synthesis, Pharmacological Activities, PharmaceuticalPreparation and Metabolism of Ginsenoside Rh2

Xiaoyun Chai, Qingguo Meng, Li Liu, Huiyun Wang, Sheng Jiang, Feng-Lan Zhao

2021Mini-Reviews in Medicinal Chemistry16 citationsDOI

Abstract

Ginsenoside Rh2 (3β-O-Glc-protopanaxadiol), a trace but characteristic pharmacological component of red ginseng, exhibited versatile pharmacological activities, such as antitumor effects, improved cardiac function and fibrosis, anti-inflammatory effects, antibiosis and excellent medicinal potential. In recent years, increased research has been performed on the biocatalytic synthesis of ginsenoside Rh2. In this paper, advances in the biocatalytic synthesis, pharmacological activities, pharmaceutical preparation and metabolism of ginsenoside Rh2 are reviewed.

Topics & Concepts

GinsengProtopanaxadiolGinsenosideChemistryPharmacologyAntibiosisTraditional medicineMedicineBiologyGeneticsPathologyAlternative medicineBacteriaGinseng Biological Effects and ApplicationsBiological and pharmacological studies of plantsPharmacological Effects of Natural Compounds