Multiscale Simulation Reveals Passive Proton Transport Through SERCA on the Microsecond Timescale
Chenghan Li, Zhi Yue, L. Michel Espinoza-Fonseca, Gregory A. Voth
Topics & Concepts
SERCABiophysicsProtonProton transportEndoplasmic reticulumATP hydrolysisIon transporterChemistryMicrosecondCytoplasmUmbrella samplingATPaseMolecular dynamicsBiochemistryMembranePhysicsBiologyEnzymeAstronomyComputational chemistryQuantum mechanicsNanopore and Nanochannel Transport StudiesSpectroscopy and Quantum Chemical StudiesIon channel regulation and function