Addition–Fragmentation Ring‐Opening Polymerization of Bio‐Based Thiocarbonyl <scp>l</scp>‐Lactide for Dual Degradable Vinyl Copolymers
Ryoya Kamiki, Tomohiro Kubo, Kotaro Satoh
Abstract
This study is designed to synthesize novel degradable polymers by radical addition-fragmentation ring-opening copolymerization of bio-based thiocarbonyl compounds with various vinyl monomers. Thiocarbonyl l-lactide is capable of radical copolymerization with acrylates and styrene via radical addition to the carbon-sulfur double bonds followed by ring-opening as well as controlled copolymerization in conjunction with the reversible addition-fragmentation chain transfer (RAFT) process. The obtained polymers possess ring-opened thioester and ring-retained thioacetal functionalities in the backbone, both of which could be cleaved under appropriate conditions with different chemical stimuli.
Topics & Concepts
CopolymerPolymer chemistryChain transferRing-opening polymerizationMonomerPolymerizationPolymerRaftReversible addition−fragmentation chain-transfer polymerizationRadical polymerizationVinyl polymerChemistryLactideMaterials scienceOrganic chemistrybiodegradable polymer synthesis and propertiesAdvanced Polymer Synthesis and CharacterizationAntimicrobial agents and applications