Kv1.3 channel blockade alleviates cerebral ischemia/reperfusion injury by reshaping M1/M2 phenotypes and compromising the activation of NLRP3 inflammasome in microglia
Dai-Chao Ma, Nannan Zhang, Yina Zhang, Dawei Chen
Topics & Concepts
MicrogliaNeuroinflammationInflammasomeReperfusion injuryPharmacologyIn vivoIschemiaMedicineBlockadeWestern blotInflammationImmunologyChemistryBiologyInternal medicineReceptorBiochemistryGeneBiotechnologyInflammasome and immune disordersNeuroinflammation and Neurodegeneration MechanismsExtracellular vesicles in disease