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Identification of triazolopyridine derivatives as a new class of AhR agonists and evaluation of anti-psoriasis effect in a mouse model

Chenyu Tian, Guo Zhang, Ziyi Xia, Nanjun Chen, Shengyong Yang, Linli Li

2022European Journal of Medicinal Chemistry22 citationsDOIOpen Access PDF

Topics & Concepts

PsoriasisAryl hydrocarbon receptorChemistryIn vivoPharmacologyDrugTranscription factorImmune systemEC50In vitroStereochemistryBiochemistryImmunologyGeneMedicineBiologyBiotechnologyPsoriasis: Treatment and PathogenesisImmunotherapy and Immune ResponsesT-cell and B-cell Immunology
Identification of triazolopyridine derivatives as a new class of AhR agonists and evaluation of anti-psoriasis effect in a mouse model | Litcius