Bone tissue engineering supported by bioprinted cell constructs with endothelial cell spheroids
Won-Jin Kim, Chul Ho Jang, GeunHyung Kim
Abstract
In bone tissue engineering, efficient formation of vascularized bone tissue is a challenging issue. Here, we introduce a new strategy for effectively using multiple cells laden in a hybrid structure, such as endothelial cell (EC) spheroids and homogeneously distributed human adipose stem cells (hASCs) for bone regeneration.
Topics & Concepts
Spheroid3D bioprintingCell biologyTissue engineeringCellStem cellBiomedical engineeringChemistryIn vivoStromal cellMicroscale chemistryIn vitroBiologyMedicineBiotechnologyCancer researchBiochemistryMathematicsMathematics education3D Printing in Biomedical ResearchBone Tissue Engineering MaterialsMesenchymal stem cell research