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Structure-based engineering of the midnolin-proteasome pathway for targeted protein degradation

Hongyang Wang, Ying Zheng, Tiantian Wang, Xue Zhang, Peipei Wang, Chuancun Wei, Hongyue Li, Quan Wang, Lu Zhang, Xisong Ke, Wenqing Xu

2025Protein & Cell6 citationsDOIOpen Access PDF

Abstract

Hongyang Wang, Ying Zheng, Tiantian Wang, Xue Zhang, Peipei Wang, Chuancun Wei, Hongyue Li, Quan Wang, Lu Zhang, Xisong Ke, Wenqing Xu; Structure-based eng

Topics & Concepts

ProteasomeProtein degradationDegradation (telecommunications)Human geneticsDevelopmental biologyBiologyCell biologyComputational biologyGeneticsEngineeringGeneTelecommunicationsUbiquitin and proteasome pathwaysProtein Degradation and InhibitorsPeptidase Inhibition and Analysis