Robust gene expression programs underlie recurrent cell states and phenotype switching in melanoma
Jasper Wouters, Zeynep Kalender Atak, Liesbeth Minnoye, Katina I. Spanier, Maxime De Waegeneer, Carmen Bravo González‐Blas, David Mauduit, Kristofer Davie, Gert Hulselmans, Ahmad Najem, Michael Dewaele, Dennis Pedri, Florian Rambow, Samira Makhzami, Valerie Christiaens, Frederik Ceyssens, Ghanem Ghanem, Jean‐Christophe Marine, Suresh Poovathingal, Stein Aerts
Topics & Concepts
PhenotypePhenotypic switchingCell biologyGeneGene expressionBiologyMelanomaCellRegulation of gene expressionGeneticsSingle-cell and spatial transcriptomicsCAR-T cell therapy researchCRISPR and Genetic Engineering