1p/19q co-deletion status is associated with distinct tumor-associated macrophage infiltration in IDH mutated lower-grade gliomas
Yanyu Zhang, Yuan Xie, Liqun He, Jiefu Tang, Qiyuan He, Qingze Cao, Langjun Cui, Wei Guo, Kai Hua, Anna Dimberg, Liang Wang, Lei Zhang
Topics & Concepts
Isocitrate dehydrogenaseGliomaBiologyTranscriptomeCancer researchTumor-associated macrophagePhenotypeTumor progressionIDH1Tumor microenvironmentGeneGeneticsGene expressionMutationBiochemistryTumor cellsEnzymeGlioma Diagnosis and TreatmentImmune cells in cancerNeurogenesis and neuroplasticity mechanisms