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Beneficial effects of QTC-4-MeOBnE in an LPS-induced mouse model of depression and cognitive impairments: The role of blood-brain barrier permeability, NF-κB signaling, and microglial activation

Mariana G. Fronza, Rodolfo Baldinotti, Jenifer Fetter, Suzan Gonçalves Rosa, Manoela Sacramento, Cristina W. Nogueira, Diego Alves, Domenico Praticò, Lucielli Savegnago

2021Brain Behavior and Immunity35 citationsDOI

Topics & Concepts

NeuroinflammationTail suspension testBehavioural despair testNeurogenesisPharmacologyHippocampusMedicineNeuroscienceChemistryInternal medicinePsychologyInflammationAntidepressantNeuroinflammation and Neurodegeneration MechanismsTryptophan and brain disordersAlzheimer's disease research and treatments
Beneficial effects of QTC-4-MeOBnE in an LPS-induced mouse model of depression and cognitive impairments: The role of blood-brain barrier permeability, NF-κB signaling, and microglial activation | Litcius