Synthesis of the first 2-hydroxyanthraquinone substituted cyclotriphosphazenes and their cytotoxic properties
Gönül Yenilmez Çiftçi, Nagihan Bayık, Esra Tanrıverdi Eçik, Elif Şenkuytu, Maşuk Akşahin, Tuba Yıldırım
Abstract
New 2-hydroxyanthraquinone based cyclotriphosphazenes were prepared and their cytotoxic effects were investigated in MCF-7 (breast cancer), MCF-12A (normal breast epithelium), DLD-1 (colon cancer), and CD-18Co (normal colon epithelium) cell lines.
Topics & Concepts
ChemistryCytotoxic T cellEpitheliumCytotoxicityCancer researchBiochemistryPathologyIn vitroBiologyMedicineSynthesis of Organic CompoundsBioactive Compounds and Antitumor AgentsNatural Compound Pharmacology Studies