Litcius/Paper detail

MicroRNA targeting: A novel therapeutic intervention for ovarian cancer

Elmira Roshani Asl, Sajed Sarabandi, Behrouz Shademan, Kourosh Dalvandi, Golshan Sheikhansari, Alireza Nourazarian

2023Biochemistry and Biophysics Reports13 citationsDOIOpen Access PDF

Abstract

Ovarian cancer, a perilous form of cancer affecting the female reproductive system, exhibits intricate communication networks that contribute to its progression. This study aims to identify crucial molecular abnormalities linked to the disease to enhance diagnostic and therapeutic strategies. In particular, we investigate the role of microRNAs (miRNAs) as diagnostic biomarkers and explore their potential in treating ovarian cancer. By targeting miRNAs, which can influence multiple pathways and genes, substantial therapeutic benefits can be attained. In this review we want to shed light on the promising application of miRNA-based interventions and provide insights into the specific miRNAs implicated in ovarian cancer pathogenesis.

Topics & Concepts

microRNAOvarian cancerDiseaseCancerBiologyBioinformaticsComputational biologyCancer researchMedicineGeneInternal medicineGeneticsMicroRNA in disease regulationCircular RNAs in diseasesCancer-related molecular mechanisms research