Physicochemical properties and bioactivity of polysaccharides from <i>Isaria cicadae Miquel</i> with different extraction processes: effects on gut microbiota and immune response in mice
Wan Wang, Cong Xu, Zhijing Liu, Liya Gu, Jiage Ma, Juncai Hou, Zhanmei Jiang
Abstract
decreased significantly. Meanwhile, U-ICM significantly promotes the expression of tight junction protein and the production of cytokines, indicating that U-ICM had the function of enhancing the intestinal barrier and regulating the host immune response. In conclusion, U-ICM as dietary fiber has the potential to be developed as a gut health-promoting prebiotic component or functional food. This research provided a valuable resource for further exploring the structure-activity relationship and prebiotic activity of ICMs.
Topics & Concepts
PrebioticGut floraPolysaccharideImmune systemAntioxidantBiologyBacteroidesLactobacillusFood scienceAkkermansiaFunctional foodChemistryMicrobiologyBiochemistryBacteriaFermentationImmunologyGeneticsPolysaccharides and Plant Cell WallsProbiotics and Fermented FoodsProteins in Food Systems