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Anti-complement C5 therapy with eculizumab in three cases of critical COVID-19

Jeffrey Laurence, J. Justin Mulvey, Madhav Seshadri, Alexandra C. Racanelli, Joanna Harp, Edward J. Schenck, Dana Zappetti, Evelyn M. Horn, Cynthia M. Magro

2020Clinical Immunology128 citationsDOIOpen Access PDF

Topics & Concepts

EculizumabMedicineComplement systemComplement component 5Lectin pathwayAcute kidney injuryRespiratory failureImmunologyAtypical hemolytic uremic syndromeInternal medicineGastroenterologyAntibodyAlternative complement pathwayCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchComplement system in diseases
Anti-complement C5 therapy with eculizumab in three cases of critical COVID-19 | Litcius