Astragaloside IV prevents Aβ1-42 oligomers-induced memory impairment and hippocampal cell apoptosis by promoting PPARγ/BDNF signaling pathway
Xuncui Wang, Wen Xu, Hejuntao Chen, Weizu Li, Weiping Li, Guoqi Zhu
Topics & Concepts
Tropomyosin receptor kinase BNeurotrophic factorsNeurotoxicityHippocampal formationBrain-derived neurotrophic factorPeroxisome proliferator-activated receptorApoptosisChemistryReceptorHippocampusSignal transductionEndocrinologyPharmacologyInternal medicineBiologyMedicineBiochemistryToxicityAlzheimer's disease research and treatmentsMedicinal Plants and NeuroprotectionNeuroinflammation and Neurodegeneration Mechanisms