Contribution of the NLRP3/IL-1β axis to impaired vasodilation in sepsis through facilitation of eNOS proteolysis and the protective role of melatonin
Shupeng Hu, Qiangzhong Pi, Minghao Luo, Zhe Cheng, Xiaoxue Liang, Suxin Luo, Yong Xia
Topics & Concepts
EnosEndothelial dysfunctionInternal medicineNitric oxideMelatoninVasodilationSepsisEndocrinologyEndotheliumNitric oxide synthaseMedicineInflammasome and immune disordersCircadian rhythm and melatoninEicosanoids and Hypertension Pharmacology