Tailored Doxycycline Hyclate Loaded In Situ Gel for the Treatment of Periodontitis: Optimization, In Vitro Characterization, and Antimicrobial Studies
Ketan M. Ranch, Furqan A. Maulvi, Akshay R. Koli, Ditixa T. Desai, Rajesh K. Parikh, Dinesh O. Shah
Topics & Concepts
DoxycyclinePoloxamer 407PoloxamerPolyethylene glycolIn situChitosanBox–Behnken designAntimicrobialChromatographyMinimum inhibitory concentrationChemistryMaterials scienceAntibioticsPolymerResponse surface methodologyBiochemistryCopolymerOrganic chemistryOral microbiology and periodontitis researchAdvanced Drug Delivery SystemsSalivary Gland Disorders and Functions