Enhanced statistical sampling reveals microscopic complexity in the talin mechanosensor folding energy landscape
Rafael Tapia‐Rojo, Marc Mora, Stephanie Board, Jane Walker, Rajaa Boujemaa‐Paterski, Ohad Medalia, Sergi Garcia-Manyes
Topics & Concepts
Energy landscapeFolding (DSP implementation)PhysicsIntrinsically disordered proteinsConformational ensemblesProtein foldingStatistical physicsMagnetic tweezersMolecular dynamicsStatistical mechanicsEnergy (signal processing)BiophysicsMoleculeBiologyQuantum mechanicsThermodynamicsNuclear magnetic resonanceEngineeringElectrical engineeringProtein Structure and DynamicsLipid Membrane Structure and BehaviorForce Microscopy Techniques and Applications