Litcius/Paper detail

Redefining the Mechanistic Scenario of Carbon−Sulfur Nucleophilic Coupling via High‐Valent Cp*Co<sup>IV</sup> Species

Sara López, Sara Martı́nez de Salinas, Felipe A. Garcés‐Pineda, Andrea Moneo‐Corcuera, José Ramón Galán‐Mascarós, Feliu Maseras, Mónica H. Pérez‐Temprano

2021Angewandte Chemie International Edition22 citationsDOI

Abstract

Abstract The potential access to Co IV species for promoting transformations that are particularly challenging at Co III still remains underexploited in the context of Cp*Co‐catalyzed C−H functionalization reactions. Herein, we disclose a combined experimental and computational strategy for uncovering the participation of Cp*Co IV species in a Cp*Co‐mediated C−S bond‐reductive elimination. These studies support the intermediacy of high‐valent Cp*Co species in C−H functionalization reactions, under oxidative conditions, when involving nucleophilic coupling partners.

Topics & Concepts

NucleophileChemistryReductive eliminationSulfurContext (archaeology)Surface modificationCombinatorial chemistryNucleophilic additionRedoxCatalysisMedicinal chemistryStereochemistryOrganic chemistryPhysical chemistryBiologyPaleontologyCatalytic C–H Functionalization MethodsSulfur-Based Synthesis TechniquesSynthesis and Catalytic Reactions