Biodistribution and Non-linear Gene Expression of mRNA LNPs Affected by Delivery Route and Particle Size
Jiaxing Di, Zhili Du, Kangzeng Wu, Shanshan Jin, Xun Wang, Tonglei Li, Yuhong Xu
Topics & Concepts
BiodistributionLuciferaseChemistryMolecular biologyGene expressionMessenger RNATransgeneTransfectionBioluminescence imagingGene deliverySpleenCell biologyBiophysicsBiologyGeneBiochemistryIn vitroImmunologyRNA Interference and Gene DeliveryNanoparticle-Based Drug DeliveryLipid Membrane Structure and Behavior