SOS1-inspired hydrocarbon-stapled peptide as a pan-Ras inhibitor
Anpeng Li, Xiang Li, Jihua Zou, Xiaobin Zhuo, Daiwen Chen, Xiaoyun Chai, Conghao Gai, Weiheng Xu, Qingjie Zhao, Yan Zou, Yan Zou
Topics & Concepts
PeptideChemistryMutationCancer researchCell growthKinaseSignal transductionCell biologyBiochemistryBiologyGeneProtein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancerMelanoma and MAPK Pathways