Pharmacological mechanisms of norcantharidin against hepatocellular carcinoma.
Zhong‐Ming Qian, Yunjin Chen, Yu-Xin Bao
Abstract
and CDC25C, and by inhibiting the c-Met-mTOR and JAK/STAT3 signaling pathways, reversing the methylation of RASSF1A gene, and activating TRAIL-R2/DR5 signal transduction.
Topics & Concepts
AutophagyCancer researchMetastasisApoptosisProgrammed cell deathHepatocellular carcinomaPI3K/AKT/mTOR pathwaySorafenibSTAT3C-MetSignal transductionMitosisCytotoxic T cellMedicineCancerBiologyCell biologyInternal medicineHepatocyte growth factorBiochemistryIn vitroReceptorBeetle Biology and Toxicology Studies