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Cone-shaped optical fiber tip for cost-effective digital lensless holographic microscopy

Brayan Patiño-Jurado, Juan F. Botero-Cadavid, Jorge Garcı́a-Sucerquia

2020Applied Optics27 citationsDOI

Abstract

In this work, the development and application of a cost-effective and robust digital lensless holographic microscopy (DLHM) system is presented. In the simple architecture of DLHM based on a point source and a digital camera, the production of the former is introduced by means of an engineered step-index optical fiber with a cone-shaped end tip. The conventional and regularly expensive point source in DLHM is produced by means of a high-numerical-aperture microscope objective and a metallic wavelength-sized pinhole. The proposed replacement renders to DLHM additional simplicity of building, in addition to mechanical stability and robustness, and further reduces the cost of the microscope. The simplified cost-effective DLHM architecture is utilized for imaging resolution test targets and samples of human blood and pond water, revealing competitive mechanical stability and trustable phase images of the imaged specimens.

Topics & Concepts

OpticsDigital holographic microscopyMicroscopePinhole (optics)HolographyMaterials scienceMicroscopyDigital holographyOptical microscopeNumerical apertureLight sheet fluorescence microscopyComputer scienceWavelengthScanning electron microscopeScanning confocal electron microscopyPhysicsDigital Holography and MicroscopyImage Processing Techniques and ApplicationsOrbital Angular Momentum in Optics
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