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Pramipexole and Lactoferrin ameliorate Cyclophosphamide-Induced haemorrhagic cystitis via targeting Sphk1/S1P/MAPK, TLR-4/NF-κB, and NLRP3/caspase-1/IL-1β signalling pathways and modulating the Nrf2/HO-1 pathway

Nayira A. Abdel Baky, Aya H. Al‐Najjar, Hemat A. Elariny, Amany Said Sallam, Asmaa A. Mohammed

2022International Immunopharmacology23 citationsDOI

Topics & Concepts

MAPK/ERK pathwayPharmacologyPramipexoleChemistryLactoferrinSignal transductionMedicineBiochemistryParkinson's diseaseInternal medicineDiseaseChemotherapy-induced organ toxicity mitigationPolyomavirus and related diseasesBladder and Urothelial Cancer Treatments
Pramipexole and Lactoferrin ameliorate Cyclophosphamide-Induced haemorrhagic cystitis via targeting Sphk1/S1P/MAPK, TLR-4/NF-κB, and NLRP3/caspase-1/IL-1β signalling pathways and modulating the Nrf2/HO-1 pathway | Litcius