TLR7 and RIG-I dual-adjuvant loaded nanoparticles drive broadened and synergistic responses in dendritic cells in vitro and generate unique cellular immune responses in influenza vaccination
Randall Toy, M. Cole Keenum, Pallab Pradhan, Katelynn Phang, Patrick Chen, Chinwendu Chukwu, Lily Anh H. Nguyen, Jiaying Liu, Sambhav Jain, Gabrielle Kozlowski, Justin Hosten, Mehul S. Suthar, Krishnendu Roy
Topics & Concepts
TLR7Immune systemAdjuvantDendritic cellAntigenImmunologyAcquired immune systemAntigen-presenting cellBiologyCross-presentationCD8T cellInnate immune systemToll-like receptorInfluenza Virus Research StudiesImmune Response and Inflammationinterferon and immune responses