TRIM7 inhibits enterovirus replication and promotes emergence of a viral variant with increased pathogenicity
Wenchun Fan, Katrina B. Mar, Levent Sari, Ilona K. Gaszek, Qiang Cheng, Bret M. Evers, John M. Shelton, Mary Wight‐Carter, Daniel J. Siegwart, Milo M. Lin, John W. Schoggins
Topics & Concepts
BiologyViral replicationEffectorVirologyUbiquitinUbiquitin ligaseVirusProteasomeHost factorViral structural proteinCoxsackievirusPicornavirusInterferonViral entryEnterovirus 71Viral pathogenesisMutationViral proteinCell biologyEnterovirusGeneticsRNAGeneinterferon and immune responsesViral Infections and Immunology ResearchCytomegalovirus and herpesvirus research