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Efficient Nuclease-Directed Integration of Lentivirus Vectors into the Human Ribosomal DNA Locus

Diana Schenkwein, Saira Afzal, Alisa Nousiainen, Manfred Schmidt, Seppo Ylä‐Herttuala

2020Molecular Therapy31 citationsDOIOpen Access PDF

Topics & Concepts

Homing endonucleaseInsertional mutagenesisBiologyChromatinTransgeneGeneticsMinicircleGeneMolecular biologyCell biologyIntronGenomeVirus-based gene therapy researchCRISPR and Genetic EngineeringViral Infections and Immunology Research
Efficient Nuclease-Directed Integration of Lentivirus Vectors into the Human Ribosomal DNA Locus | Litcius