Renal Involvement in COVID-19: A Review of the Literature
Marco Giuseppe Migliaccio, Marco Di Mauro, Riccardo Ricciolino, Giorgio Spiniello, Vincenzo Carfora, Nicoletta Verde, Filiberto Fausto Mottola, Nicola Coppola
Abstract
Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting immunity response. We summarized the evidence of the literature on the prevalence of kidney involvement, on the pathogenic pathways and on its management.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MedicineVirologyInternal medicineInfectious disease (medical specialty)OutbreakDiseaseMuscle and Compartmental DisordersCOVID-19 Clinical Research StudiesCOVID-19 Impact on Reproduction