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β1-Integrin binding to collagen type 1 transmits breast cancer cells into chemoresistance by activating ABC efflux transporters

Fabian Baltes, Vladlena Pfeifer, Katja Silbermann, Julia Caspers, Kathleen Wantoch von Rekowski, Martin Schlesinger, Gerd Bendas

2020Biochimica et Biophysica Acta (BBA) - Molecular Cell Research82 citationsDOI

Topics & Concepts

ATP-binding cassette transporterEffluxChemistryAbcg2DoxorubicinTransporterPharmacologyMitoxantroneDownregulation and upregulationCancer cellCancer researchMultiple drug resistanceGene knockdownCancerBiochemistryBiologyMedicineInternal medicineApoptosisChemotherapyAntibioticsGeneDrug Transport and Resistance MechanismsCell Adhesion Molecules ResearchRadiopharmaceutical Chemistry and Applications
β1-Integrin binding to collagen type 1 transmits breast cancer cells into chemoresistance by activating ABC efflux transporters | Litcius