Synthesis, molecular modeling, selective aldose reductase inhibition and hypoglycemic activity of novel meglitinides
Manar G. Salem, Yasmine M. Abdel Aziz, Marwa Elewa, Mohamed S. Nafie, Hosam A. Elshihawy, Mohamed M. Said
Topics & Concepts
Aldose reductaseChemistryAldehyde ReductaseAldose reductase inhibitorAcetamideRhodanineDocking (animal)BiochemistryIn vivoIC50RepaglinidePharmacologyStereochemistryIn vitroEnzymeMetforminInsulinEndocrinologyOrganic chemistryNursingBiotechnologyBiologyMedicineAldose Reductase and TaurineAdenosine and Purinergic SignalingCholinesterase and Neurodegenerative Diseases