Reconstructed Single-Cell Fate Trajectories Define Lineage Plasticity Windows during Differentiation of Human PSC-Derived Distal Lung Progenitors
Killian Hurley, Jun Ding, Carlos Villacorta-Martín, Michael J. Herriges, Anjali Jacob, Marall Vedaie, Konstantinos D. Alysandratos, Yuliang Sun, Chieh Hubert Lin, Rhiannon B. Werder, Jessie Huang, Andrew A. Wilson, Aditya Mithal, Gustavo Mostoslavsky, Irene Oglesby, Ignacio Caballero, Susan H. Guttentag, Farida Ahangari, Naftali Kaminski, Alejo Rodriguez-Fraticelli, Fernando D. Camargo, Ziv Bar‐Joseph, Darrell N. Kotton
Topics & Concepts
BiologyProgenitor cellCell fate determinationWnt signaling pathwayCell biologyProgenitorCellular differentiationStem cellFate mappingInduced pluripotent stem cellEmbryonic stem cellGeneticsSignal transductionGeneTranscription factorNeonatal Respiratory Health ResearchSingle-cell and spatial transcriptomicsRenal and related cancers