APOE2, E3, and E4 differentially modulate cellular homeostasis, cholesterol metabolism, and inflammatory response in isogenic iPSC-derived astrocytes
Sherida M. de Leeuw, Aron W.T. Kirschner, Karina Lindner, Ruslan Rust, Vanessa Budny, Witold Wolski, Anne‐Claude Gavin, Roger M. Nitsch, Christian Tackenberg
Abstract
In the initial version of this article, there was an error in the merged image for APOE3 in Figure 1E. While all individual images for S100b and GJA1 were displayed correctly, we accidentally merged APOE3 GJA1 with APOE2 S100b (and not with the S100b image of APOE3). However, this error did not affect the figure’s meaning or conclusion. The correct merged GJA1/S100b staining for APOE3 iAstrocytes has now been included in the article online and below. No correction of the text or figure legend was necessary.
Topics & Concepts
BiologyApolipoprotein EInduced pluripotent stem cellHomeostasisCell biologyLipid metabolismNeuroscienceGeneticsEndocrinologyInternal medicineGeneDiseaseMedicineEmbryonic stem cellFerroptosis and cancer prognosisImmune responses and vaccinationsExtracellular vesicles in disease