Litcius/Paper detail

Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1

Zhiping Feng, Marisa E. Hom, Thomas E. Bearrood, Zachary C. Rosenthal, Daniel Fernández, Alison E. Ondrus, Yuchao Gu, Aaron K. McCormick, Madeline Tomaske, Cody R. Marshall, Toni Kline, Che‐Hong Chen, Daria Mochly‐Rosen, Calvin J. Kuo, James Chen

2022Nature Chemical Biology60 citationsDOIOpen Access PDF

Topics & Concepts

Aldehyde dehydrogenaseALDH2PharmacophoreBiologyColorectal cancerSmall moleculeBiochemistryCancerCancer researchEnzymeGeneticsCancer, Hypoxia, and MetabolismCancer Cells and MetastasisPolyamine Metabolism and Applications