A Co-Doped Fe<sub>3</sub>O<sub>4</sub> Nanozyme Shows Enhanced Reactive Oxygen and Nitrogen Species Scavenging Activity and Ameliorates the Deleterious Effects of Ischemic Stroke
Yunsheng Liu, Xiaojun Wang, Xiangzhu Li, Shanshan Qiao, Guodong Huang, Dirk M. Hermann, Thorsten R. Doeppner, Muling Zeng, Wei Liu, Gelin Xu, Lijie Ren, Yuan Zhang, Wenlan Liu, Eudald Casals, Weiping Li, Yachao Wang
Abstract
nanozyme was efficacious in two well-characterized ischemic stroke models provides strong evidence that it represents a powerful tool for targeting oxidative and nitrosative stress in the ischemic brain.
Topics & Concepts
Materials scienceScavengingReactive oxygen speciesNitrogenOxygenReactive nitrogen speciesAntioxidantBiochemistryBiologyOrganic chemistryChemistryAdvanced Nanomaterials in CatalysisElectrochemical sensors and biosensorsNeuroinflammation and Neurodegeneration Mechanisms