An Improved P<sup>III</sup>/P<sup>V</sup>═O-Catalyzed Reductive C–N Coupling of Nitroaromatics and Boronic Acids by Mechanistic Differentiation of Rate- and Product-Determining Steps
Gen Li, Trevor V. Nykaza, Julian C. Cooper, Antonio Ramı́rez, Michael R. Luzung, Alexander T. Radosevich
Abstract
hydrolysis. The method thus described constitutes a mechanistically well-defined and operationally robust main-group complement to the current workhorse transition-metal-based methods for catalytic intermolecular C-N coupling.
Topics & Concepts
ChemistryDeoxygenationCatalysisHomolysisPhotochemistryDissociation (chemistry)Coupling reactionMedicinal chemistryPhysical chemistryOrganic chemistryRadicalCatalytic Cross-Coupling ReactionsCatalytic C–H Functionalization MethodsOrganoboron and organosilicon chemistry