Litcius/Paper detail

LuxT Is a Global Regulator of Low-Cell-Density Behaviors, Including Type III Secretion, Siderophore Production, and Aerolysin Production, in Vibrio harveyi

Michaela J. Eickhoff, Chenyi Fei, Jian-Ping Cong, Bonnie L. Bassler

2022mBio15 citationsDOIOpen Access PDF

Abstract

species, ubiquitous marine bacteria that often cause disease. We characterize the mechanisms by which LuxT controls genes involved in virulence and nutrient acquisition. We show that LuxT functions in parallel with a set of regulators of the bacterial cell-to-cell communication process called quorum sensing to promote V. harveyi behaviors at low cell density.

Topics & Concepts

Vibrio harveyiBiologyRegulatorQuorum sensingAutoinducerVibrioGeneSiderophoreType three secretion systemTranscriptional regulationRepressorRegulator geneGeneticsMicrobiologyRegulation of gene expressionCell biologyGene expressionBacteriaVirulenceVibrio bacteria research studiesBacterial biofilms and quorum sensingBacterial Genetics and Biotechnology