Suspended particulate matter promotes epithelial-to-mesenchymal transition in alveolar epithelial cells via TGF-β1-mediated ROS/IL-8/SMAD3 axis
Shahrzad Molavinia, Dian Dayer, Mohammad Javad Khodayar, Gholamreza Goudarzi, Maryam Salehcheh
Topics & Concepts
VimentinEpithelial–mesenchymal transitionWestern blotA549 cellTransforming growth factorChemistryOxidative stressMesenchymal stem cellPulmonary fibrosisReactive oxygen speciesInterleukinInflammationMolecular biologyFibrosisCell biologyBiologyCellImmunologyPathologyMedicineTransition (genetics)CytokineBiochemistryImmunohistochemistryGeneOccupational and environmental lung diseasesInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisChronic Obstructive Pulmonary Disease (COPD) Research