Increased Oxidative Stress Tolerance of a Spontaneously Occurring <i>perR</i> Gene Mutation in Streptococcus mutans UA159
Jessica K. Kajfasz, Peter Zuber, Tridib Ganguly, Jacqueline Abranches, José A. Lemos
Abstract
A resident of the human oral biofilm, Streptococcus mutans is one of the major bacterial pathogens associated with dental caries. This report highlights a spontaneously occurring mutation within the laboratory strain S. mutans UA159 found in the coding region of perR , a gene encoding a transcriptional repressor associated with peroxide tolerance.
Topics & Concepts
Streptococcus mutansBiologyGeneRepressorGeneticsMicrobiologyBiofilmStrain (injury)MutationTranscription factorBacteriaAnatomyInfective Endocarditis Diagnosis and ManagementOral microbiology and periodontitis researchGenomics and Phylogenetic Studies