Life cycle analysis and sustainability comparison of reversed phase high performance liquid chromatography and carbon dioxide-containing chromatography of small molecule pharmaceuticals
Brian N. Fitch, Rebekah Gray, Martin Beres, Michael B. Hicks, William Farrell, Christine Aurigemma, Susan V. Olesik
Abstract
Life cycle analysis allows comparison of RP-HPLC to SFC.
Topics & Concepts
High-performance liquid chromatographyChemistryChromatographyCarbon dioxidePhase (matter)MoleculeReversed-phase chromatographyOrganic chemistryChemistry and Chemical EngineeringProcess Optimization and IntegrationAnalytical Chemistry and Chromatography