Engineering a pathological tau-targeted nanochaperone for selective and synergetic inhibition of tau pathology in Alzheimer's Disease
Linlin Xu, Yuxun Ding, Feihe Ma, Yue Chen, Guidong Chen, Lin Zhu, Jiafu Long, Rujiang Ma, Yang Liu, Jianfeng Liu, Fan Huang, Linqi Shi
Topics & Concepts
IntracellularTau proteinTau pathologyNeuroscienceTauopathyCytosolChemistryCell biologyAlzheimer's diseaseCytoplasmNeurodegenerationDiseaseBiologyMedicineBiochemistryPathologyEnzymeAlzheimer's disease research and treatmentsEndoplasmic Reticulum Stress and DiseaseHeat shock proteins research