Metabolic engineering for optimized CAR-T cell therapy
Sarah McPhedran, Gillian Carleton, Julian J. Lum
Topics & Concepts
Chimeric antigen receptorCytotoxicityImmune systemMetabolic pathwayBiologyT cellComputational biologyCellImmunotherapyGenome editingMetabolic engineeringFunction (biology)Genetic enhancementBioinformaticsCancer researchImmunologyGeneGenomeCell biologyGeneticsIn vitroCAR-T cell therapy researchImmune Cell Function and InteractionCRISPR and Genetic Engineering