Corneal graft rejection following COVID-19 vaccine
Konstantinos Rallis, Darren Shu Jeng Ting, Dalia G. Said, Harminder S. Dua
Abstract
COVID-19 has affected >100 million with >2 million deaths worldwide. A number of effective mRNA-based [ 1 ] and viral vector-based vaccines [ 2 ] have been developed and deployed. However, as COVID-19 vaccines have been shown to induce strong immune responses [ 3 ], there remains a hypothetical concern whether the vaccine could increase the risk of transplant rejection in non-immunosuppressed patients. In this report, we highlight a case of acute corneal allograft rejection shortly after the administration of COVID-19 vaccine.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakMedicineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyOphthalmologyBetacoronavirusPathologyInfectious disease (medical specialty)DiseaseOutbreakRetinal and Optic ConditionsSARS-CoV-2 and COVID-19 ResearchCOVID-19 and healthcare impacts