TRIM3 facilitates ferroptosis in non-small cell lung cancer through promoting SLC7A11/xCT K11-linked ubiquitination and degradation
Zhangjie Wang, Na Shen, Ziao Wang, Lei Yu, Song Yang, Yang Wang, Yu Liu, Gaohua Han, Qi Zhang
Topics & Concepts
Ubiquitin ligaseUbiquitinCancer researchCarcinogenesisLung cancerAdenocarcinomaCellSuppressorProgrammed cell deathCancerBiologyCell biologyChemistryApoptosisMedicineInternal medicineBiochemistryGeneGeneticsFerroptosis and cancer prognosisCancer-related molecular mechanisms researchCancer, Lipids, and Metabolism