Dual-target platinum(IV) complexes exhibit antiproliferative activity through DNA damage and induce ER-stress-mediated apoptosis in A549 cells
Meng Wang, Zhikun Liu, Xiaochao Huang, Yuanhang Chen, Yanming Wang, Jing Kong, Yong Yang, Chunhao Yu, Jin Li, Xu Wang, Heng‐Shan Wang
Topics & Concepts
CisplatinChemistryApoptosisUnfolded protein responseDNA damageOxaliplatinCancer researchNephrotoxicityCancer cellOxidative stressCarboplatinPharmacologyToxicityCancerBiochemistryChemotherapyDNAInternal medicineBiologyMedicineColorectal cancerOrganic chemistryMetal complexes synthesis and propertiesFerrocene Chemistry and ApplicationsAdvanced biosensing and bioanalysis techniques