Anti-diabetic effects of natural and modified ‘Ganzhou’ navel orange peel pectin on type 2 diabetic mice <i>via</i> gut microbiota
Chao Du, Feng Zuo, Yang Cao, Yanqing Zang
Abstract
. The phenotypes of the gut microbiome also changed accordingly, which showed that MGOP significantly inhibited the growth of Gram-negative bacteria and potential pathogenic bacteria and reversed the related complications. Taken together, our findings revealed that MGOP intake regulated lipid metabolism and oxidative stress and improved the gut health of mice, with promising effects against T2DM and related complications.
Topics & Concepts
Gut floraPectinOrange (colour)ChemistryBiologyMetabolismFood scienceBiochemistryGut microbiota and healthPolysaccharides and Plant Cell WallsMicrobial Metabolites in Food Biotechnology