An Expanded Gene Catalog of Mouse Gut Metagenomes
Jiahui Zhu, Huahui Ren, Huanzi Zhong, Xiaoping Li, Yuanqiang Zou, Mo Han, Minli Li, Lise Madsen, Karsten Kristiansen, Liang Xiao
Abstract
We established an expanded gene catalog of the mouse gut metagenome not only to increase the sample size compared to that in existing catalogs but also to provide a more comprehensive reference data set of the mouse gut microbiome for bioinformatic analysis. The expanded gene catalog comprises more than 5.8 million unique genes, as well as a wide range of taxonomic and functional information. Particularly, the analysis of metagenomic species with the expanded gene catalog reveals a great novelty of mouse gut-inhabiting microbial species. We envisage that the expanded gene catalog of the mouse gut metagenome will serve as a valuable bioinformatic resource for future gut metagenomic studies in mice.