Immunoprotection against Cryptococcosis Offered by Znf2 Depends on Capsule and the Hyphal Morphology
Jianfeng Lin, Tuyetnhu Pham, Kenton Hipsher, Nathan K. Glueck, Yumeng Fan, Xiaorong Lin
Abstract
strain to provide host protection. Our findings highlight the importance of identifying the Znf2-regulated capsular surface factors that are fundamental in host protection.
Topics & Concepts
Cryptococcus neoformansBiologyCryptococcosisMicrobiologyAntigenImmune systemVirulenceImmunologyVirologyGeneBiochemistryFungal Infections and StudiesAntifungal resistance and susceptibilityNail Diseases and Treatments